BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ribonucleoside-diphosphate reductase large subunit' and Ligand = 'BDBM50050829'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ribonucleoside-diphosphate reductase large subunit


(Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)		BDBM50050829
PNG
((S)-2-((S)-3-Carboxy-2-{(S)-2-[(S)-2-(3-isopropyl-...)
Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(=O)N1CCCC1)NC(=O)[C@@H](NC(=O)NC(C)C)C(C)C)C(O)=O
Show InChI InChI=1S/C27H46N6O9/c1-14(2)11-19(26(40)41)31-24(38)18(13-21(35)36)29-23(37)17(12-20(34)33-9-7-8-10-33)30-25(39)22(15(3)4)32-27(42)28-16(5)6/h14-19,22H,7-13H2,1-6H3,(H,29,37)(H,30,39)(H,31,38)(H,35,36)(H,40,41)(H2,28,32,42)/t17-,18-,19-,22-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 435n/an/an/an/an/an/a



Bio-Méga/Boehringer Ingelheim Research Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Herpes simplex virus (HSV) ribonucleotide reductase (RR)

J Med Chem 39: 2178-87 (1996)


Article DOI: 10.1021/jm950825x
BindingDB Entry DOI: 10.7270/Q2BG2N22
More data for this
Ligand-Target Pair