Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Scavenger receptor class B member 1 (Homo sapiens (Human)) | BDBM50323654 (CHEMBL1208829 | N-(5-tert-butyl-2-methoxy-3-(methy...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibition of human SR-B1 transiently expressed in human U2OS cells assessed as Dil-HDL uptake preincubated for 2 hrs followed by Dil-HDL addition me... | Bioorg Med Chem Lett 26: 1901-4 (2016) Article DOI: 10.1016/j.bmcl.2016.03.025 BindingDB Entry DOI: 10.7270/Q22R3TJ2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Scavenger receptor class B member 1 (Mus musculus) | BDBM50323654 (CHEMBL1208829 | N-(5-tert-butyl-2-methoxy-3-(methy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 770 | n/a | n/a | n/a | n/a | n/a | n/a |
Marquette University Curated by ChEMBL | Assay Description Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of [3H]cholesteryl ester uptake into cells after 2 to 3 hrs by liquid sci... | Bioorg Med Chem Lett 25: 2100-5 (2015) Article DOI: 10.1016/j.bmcl.2015.03.073 BindingDB Entry DOI: 10.7270/Q2P84DKP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Scavenger receptor class B member 1 (Mus musculus) | BDBM50323654 (CHEMBL1208829 | N-(5-tert-butyl-2-methoxy-3-(methy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 770 | n/a | n/a | n/a | n/a | n/a | n/a |
Marquette University Curated by ChEMBL | Assay Description Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in uptake of [3H]CE from [3H]CE-HDL by by liquid scintillation count... | Bioorg Med Chem Lett 25: 2594-8 (2015) Article DOI: 10.1016/j.bmcl.2015.03.074 BindingDB Entry DOI: 10.7270/Q25Q4XTV | |||||||||||
More data for this Ligand-Target Pair |