Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Secreted frizzled-related protein 1' and Ligand = 'BDBM50265548'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Secreted frizzled-related protein 1 (Homo sapiens (Human))	BDBM50265548 (CHEMBL501332 | N-[1-(N,N-Dimethylglycyl-L-prolyl)p...) Show SMILES CN(C)CC(=O)N1CCC[C@H]1C(=O)N1CCC(CC1)NS(=O)(=O)c1cc(ccc1C(F)(F)F)S(=O)(=O)c1ccccc1 |r| Show InChI InChI=1S/C27H33F3N4O6S2/c1-32(2)18-25(35)34-14-6-9-23(34)26(36)33-15-12-19(13-16-33)31-42(39,40)24-17-21(10-11-22(24)27(28,29)30)41(37,38)20-7-4-3-5-8-20/h3-5,7-8,10-11,17,19,23,31H,6,9,12-16,18H2,1-2H3/t23-/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Binding affinity to human purified SARP2 by fluorescent polarization assay				J Med Chem 52: 105-16 (2009) Article DOI: 10.1021/jm801144h BindingDB Entry DOI: 10.7270/Q2NZ87HT
					More data for this Ligand-Target Pair