Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase 24' and Ligand = 'BDBM451749'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase 24 (Homo sapiens (Human))	BDBM451749 (6-(2-amino-5-(3-(thiazol-2- yl)phenyl)pyridin-3-yl...) Show SMILES Nc1ncc(cc1-c1ccc2C(=O)NCCc2c1)-c1cccc(c1)-c1nccs1 Show InChI InChI=1S/C23H18N4OS/c24-21-20(15-4-5-19-16(11-15)6-7-25-22(19)28)12-18(13-27-21)14-2-1-3-17(10-14)23-26-8-9-29-23/h1-5,8-13H,6-7H2,(H2,24,27)(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
DANA-FARBER CANCER INSTITUTE, INC.; FONDAZIONE CENTRO SAN RAFFAELE US Patent					Assay Description Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...				US Patent US10710978 (2020) BindingDB Entry DOI: 10.7270/Q2J67KZW
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