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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase 24' and Ligand = 'BDBM451767'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase 24


(Homo sapiens (Human))
BDBM451767
PNG
(6-(2-amino-5-(5- fluorobenzo[d]thiazol-6- yl)pyrid...)
Show SMILES Nc1ncc(cc1-c1ccc2C(=O)NCCc2c1)-c1cc2scnc2cc1F
Show InChI InChI=1S/C21H15FN4OS/c22-17-8-18-19(28-10-26-18)7-15(17)13-6-16(20(23)25-9-13)11-1-2-14-12(5-11)3-4-24-21(14)27/h1-2,5-10H,3-4H2,(H2,23,25)(H,24,27)
PDB
MMDB

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PC cid
PC sid
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US Patent
n/an/a>1.00E+3n/an/an/an/an/an/a



DANA-FARBER CANCER INSTITUTE, INC.; FONDAZIONE CENTRO SAN RAFFAELE

US Patent


Assay Description
Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...


US Patent US10710978 (2020)


BindingDB Entry DOI: 10.7270/Q2J67KZW
More data for this
Ligand-Target Pair