Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase Chk1' and Ligand = 'BDBM50218711'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50218711 (8-hydroxy-3-(3-methoxy-4-nitrophenyl)-5H-dibenzo[b...) Show SMILES COc1cc(ccc1N)-c1ccc2c(Nc3ccc(O)cc3NC2=O)c1 Show InChI InChI=1S/C20H17N3O3/c1-26-19-9-12(3-6-15(19)21)11-2-5-14-17(8-11)22-16-7-4-13(24)10-18(16)23-20(14)25/h2-10,22,24H,21H2,1H3,(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant Chk1				J Med Chem 50: 4162-76 (2007) Article DOI: 10.1021/jm070105d BindingDB Entry DOI: 10.7270/Q22J6BKS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50218711 (8-hydroxy-3-(3-methoxy-4-nitrophenyl)-5H-dibenzo[b...) Show SMILES COc1cc(ccc1N)-c1ccc2c(Nc3ccc(O)cc3NC2=O)c1 Show InChI InChI=1S/C20H17N3O3/c1-26-19-9-12(3-6-15(19)21)11-2-5-14-17(8-11)22-16-7-4-13(24)10-18(16)23-20(14)25/h2-10,22,24H,21H2,1H3,(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.93E+4	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Antiproliferative activity against HeLa cells by MTS assay				J Med Chem 50: 4162-76 (2007) Article DOI: 10.1021/jm070105d BindingDB Entry DOI: 10.7270/Q22J6BKS
					More data for this Ligand-Target Pair