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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase Chk1' and Ligand = 'BDBM50224890'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase Chk1


(Homo sapiens (Human))
BDBM50224890
PNG
(7-chloro-3-oxo-8-(2-oxo-oxazolidin-3-yl)-11,16-dio...)
Show SMILES Clc1cc2NC(=O)Nc3cnc(C#N)c(OCCCCOc2cc1N1CCOC1=O)n3
Show InChI InChI=1S/C19H17ClN6O5/c20-11-7-12-15(8-14(11)26-3-6-31-19(26)28)29-4-1-2-5-30-17-13(9-21)22-10-16(24-17)25-18(27)23-12/h7-8,10H,1-6H2,(H2,23,24,25,27)
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PC cid
PC sid
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Article
PubMed
n/an/a 6n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of Chk1


Bioorg Med Chem Lett 17: 6593-601 (2007)


Article DOI: 10.1016/j.bmcl.2007.09.063
BindingDB Entry DOI: 10.7270/Q2X067WT
More data for this
Ligand-Target Pair