Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase MARK2' and Ligand = 'BDBM247045'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase MARK2 (Homo sapiens (Human))	BDBM247045 (2-((1R,3aR,6S, 7R,7aS)-5,5- difluoro-7- ((E)-2-(2&...) Show SMILES COc1ncccc1-c1ccc(\C=C\[C@@H]2[C@@H]3[C@@H](C)OC(=O)[C@]3(CC(N)=O)CC(F)(F)[C@H]2C)nc1 |r| Show InChI InChI=1S/C25H27F2N3O4/c1-14-18(21-15(2)34-23(32)24(21,11-20(28)31)13-25(14,26)27)9-8-17-7-6-16(12-30-17)19-5-4-10-29-22(19)33-3/h4-10,12,14-15,18,21H,11,13H2,1-3H3,(H2,28,31)/b9-8+/t14-,15+,18-,21-,24+/m0/s1	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	104	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description This assay measures the potency of the inventive compounds as PAR-1 receptor antagonists.Frozen HEK 293 Cells were plated in 384-well PDL coated plat...				US Patent US9701669 (2017) BindingDB Entry DOI: 10.7270/Q2PC34DS
					More data for this Ligand-Target Pair