Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM116010'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM116010 (US8633183, E-159) Show SMILES CCc1ncnc(-c2cc(F)c(C(=O)N3CCC4(COC4)CC3)c(Cl)c2)c1C#Cc1ccc(N)nc1 Show InChI InChI=1S/C27H25ClFN5O2/c1-2-22-19(5-3-17-4-6-23(30)31-13-17)25(33-16-32-22)18-11-20(28)24(21(29)12-18)26(35)34-9-7-27(8-10-34)14-36-15-27/h4,6,11-13,16H,2,7-10,14-15H2,1H3,(H2,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.530	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...				US Patent US8633183 (2014) BindingDB Entry DOI: 10.7270/Q2SX6BW4
					More data for this Ligand-Target Pair