Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-2' and Ligand = 'BDBM191091'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM191091 (US9181258, 78) Show SMILES CN(C)CCNC(=O)c1ccc(cc1)-c1c(cc2C(=O)NCC(CCO)n12)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C27H29F3N4O4/c1-33(2)12-11-31-25(36)18-8-6-17(7-9-18)24-22(19-4-3-5-21(14-19)38-27(28,29)30)15-23-26(37)32-16-20(10-13-35)34(23)24/h3-9,14-15,20,35H,10-13,16H2,1-2H3,(H,31,36)(H,32,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	90	n/a	n/a	n/a	n/a	7.5	n/a
NERVIANO MEDICAL SCIENCES S.R.L. US Patent					Assay Description The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay.Speci...				US Patent US9181258 (2015) BindingDB Entry DOI: 10.7270/Q2862F7F
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