Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-3' and Ligand = 'BDBM248996'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM248996 (US9434725, 227) Show SMILES Cc1cncc(n1)-c1cc2n(ncc2cn1)-c1ccc(C(F)F)c(n1)N1CCC[C@H](N)C1 |r| Show InChI InChI=1S/C22H22F2N8/c1-13-8-26-11-18(29-13)17-7-19-14(9-27-17)10-28-32(19)20-5-4-16(21(23)24)22(30-20)31-6-2-3-15(25)12-31/h4-5,7-11,15,21H,2-3,6,12,25H2,1H3/t15-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0190	-61.2	n/a	n/a	n/a	n/a	n/a	7.2	25
F. HOFFMANN-LA ROCHE AG US Patent					Assay Description PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...				US Patent US9434725 (2016) BindingDB Entry DOI: 10.7270/Q2CF9P1N
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