Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human)) | BDBM50299249 (1,10-Dihydropyrrolo[2,3-a]carbazole-3-carbaldehyde...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Centre National de la Recherche Scientifique; Universite Blaise Pascal-Clermont-Ferrand II US Patent | Assay Description Inhibition assay using PIM-1, PIM-2 and PIM-3. | US Patent US8481586 (2013) BindingDB Entry DOI: 10.7270/Q2ZC81GT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human)) | BDBM50299249 (1,10-Dihydropyrrolo[2,3-a]carbazole-3-carbaldehyde...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of human Pim3 using RSRHSSYPAGT as substrate | Eur J Med Chem 56: 225-236 (2012) Article DOI: 10.1016/j.ejmech.2012.08.029 BindingDB Entry DOI: 10.7270/Q2XK8GTF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human)) | BDBM50299249 (1,10-Dihydropyrrolo[2,3-a]carbazole-3-carbaldehyde...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Clermont Université Curated by ChEMBL | Assay Description Inhibition of human GST fused Pim3 expressed in Escherichia coli after 30 mins | Bioorg Med Chem 18: 6865-73 (2010) Article DOI: 10.1016/j.bmc.2010.07.036 BindingDB Entry DOI: 10.7270/Q2PK0GBZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human)) | BDBM50299249 (1,10-Dihydropyrrolo[2,3-a]carbazole-3-carbaldehyde...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Clermont Universit£ Curated by ChEMBL | Assay Description Inhibition of Pim-3 | J Med Chem 52: 6369-81 (2009) Article DOI: 10.1021/jm901018f BindingDB Entry DOI: 10.7270/Q23F4PPS | |||||||||||
More data for this Ligand-Target Pair |