Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...) | BDBM50081702 (5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 680 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer, Inc Curated by ChEMBL | Assay Description Binding affinity against 5-hydroxytryptamine 2 receptor using [125I]DOI as radioligand. | J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...) | BDBM50081702 (5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >8.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer, Inc Curated by ChEMBL | Assay Description Effect of the compound on forskolin stimulated adenylate cyclase activity at 5-HT1D receptor of guinea pig substantia nigra. | J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5 | |||||||||||
More data for this Ligand-Target Pair |