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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Short transient receptor potential channel 5' and Ligand = 'BDBM50529447'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Short transient receptor potential channel 5


(Homo sapiens (Human))		BDBM50529447
PNG
(CHEMBL4517031)
Show SMILES C[C@H]1CC[C@H](CN2CCN(CC2=O)c2cn[nH]c(=O)c2Cl)CC1 |r,wU:4.4,wD:1.0,(47.27,-39.08,;48.6,-38.32,;49.94,-39.1,;51.28,-38.34,;51.28,-36.8,;52.62,-36.04,;53.95,-36.83,;53.93,-38.37,;55.27,-39.16,;56.6,-38.39,;56.61,-36.85,;55.29,-36.07,;55.3,-34.53,;57.93,-39.17,;59.26,-38.4,;60.6,-39.16,;60.6,-40.71,;59.27,-41.48,;59.26,-43.02,;57.93,-40.71,;56.6,-41.48,;49.96,-36.02,;48.62,-36.78,)|
Show InChI InChI=1S/C16H23ClN4O2/c1-11-2-4-12(5-3-11)9-21-7-6-20(10-14(21)22)13-8-18-19-16(23)15(13)17/h8,11-12H,2-7,9-10H2,1H3,(H,19,23)/t11-,12-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 530n/an/an/an/an/an/a



Goldfinch Bio Inc.

Curated by ChEMBL


Assay Description
Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...

ACS Med Chem Lett 10: 1579-1585 (2019)


Article DOI: 10.1021/acsmedchemlett.9b00430
BindingDB Entry DOI: 10.7270/Q2DN48HF
More data for this
Ligand-Target Pair