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Found 1 hit Enz. Inhib. hit(s) with Target = 'Short transient receptor potential channel 5' and Ligand = 'BDBM50529449'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Short transient receptor potential channel 5


(Homo sapiens (Human))		BDBM50529449
PNG
(CHEMBL4449727)
Show SMILES Fc1ccc(CN2CCN(CC2=O)c2cn[nH]c(=O)c2Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C16H13ClF4N4O2/c17-14-12(6-22-23-15(14)27)24-3-4-25(13(26)8-24)7-9-1-2-10(18)5-11(9)16(19,20)21/h1-2,5-6H,3-4,7-8H2,(H,23,27)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 650n/an/an/an/an/an/a



Goldfinch Bio Inc.

Curated by ChEMBL


Assay Description
Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...

ACS Med Chem Lett 10: 1579-1585 (2019)


Article DOI: 10.1021/acsmedchemlett.9b00430
BindingDB Entry DOI: 10.7270/Q2DN48HF
More data for this
Ligand-Target Pair