Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Sialic acid-binding Ig-like lectin 7' and Ligand = 'BDBM50230647'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sialic acid-binding Ig-like lectin 7 (Homo sapiens (Human))	BDBM50230647 (CHEMBL4096201) Show SMILES [Na+].[H][C@]1(O[C@@](C[C@H](O)[C@H]1NC(C)=O)(OCCCn1cc(nn1)-c1ccc(cc1)-c1ccccc1)C([O-])=O)[C@H](O)[C@H](O)CNS(=O)(=O)CC |r| Show InChI InChI=1S/C30H39N5O10S.Na/c1-3-46(42,43)31-17-25(38)27(39)28-26(32-19(2)36)24(37)16-30(45-28,29(40)41)44-15-7-14-35-18-23(33-34-35)22-12-10-21(11-13-22)20-8-5-4-6-9-20;/h4-6,8-13,18,24-28,31,37-39H,3,7,14-17H2,1-2H3,(H,32,36)(H,40,41);/q;+1/p-1/t24-,25+,26+,27+,28+,30+;/m0./s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
G3-BioTec Curated by ChEMBL					Assay Description Binding affinity to human IgG1-fused Siglec-7-Fc assessed as inhibition of Siglec-7-Fc binding to RBC preincubated for 10 mins followed by RBC additi...				J Med Chem 60: 941-956 (2017) Article DOI: 10.1021/acs.jmedchem.6b01111 BindingDB Entry DOI: 10.7270/Q2HQ4253
					More data for this Ligand-Target Pair
Sialic acid-binding Ig-like lectin 7 (Homo sapiens (Human))	BDBM50230647 (CHEMBL4096201) Show SMILES [Na+].[H][C@]1(O[C@@](C[C@H](O)[C@H]1NC(C)=O)(OCCCn1cc(nn1)-c1ccc(cc1)-c1ccccc1)C([O-])=O)[C@H](O)[C@H](O)CNS(=O)(=O)CC |r| Show InChI InChI=1S/C30H39N5O10S.Na/c1-3-46(42,43)31-17-25(38)27(39)28-26(32-19(2)36)24(37)16-30(45-28,29(40)41)44-15-7-14-35-18-23(33-34-35)22-12-10-21(11-13-22)20-8-5-4-6-9-20;/h4-6,8-13,18,24-28,31,37-39H,3,7,14-17H2,1-2H3,(H,32,36)(H,40,41);/q;+1/p-1/t24-,25+,26+,27+,28+,30+;/m0./s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
G3-BioTec Curated by ChEMBL					Assay Description Binding affinity to human IgG1-fused Siglec-7-Fc measured after 2.5 hrs by ELISA				J Med Chem 60: 941-956 (2017) Article DOI: 10.1021/acs.jmedchem.6b01111 BindingDB Entry DOI: 10.7270/Q2HQ4253
					More data for this Ligand-Target Pair