BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Signal transducer and activator of transcription 3' and Ligand = 'BDBM50396180'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Signal transducer and activator of transcription 3 (Mus musculus (mouse))	BDBM50396180 (CHEMBL2171897) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibition of STAT3 dimerization in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction ...				J Med Chem 55: 6645-68 (2012) Article DOI: 10.1021/jm300207s BindingDB Entry DOI: 10.7270/Q2CJ8FKK
University of Southern California Curated by ChEMBL					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50396180 (CHEMBL2171897) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Central Florida Research Foundation, Inc. US Patent					Assay Description A screening process evaluated in vitro disruption of STAT3(dimer)-DNA formation through a previously published EMSA based assays, giving a valuable i...				US Patent US8969578 (2015) BindingDB Entry DOI: 10.7270/Q2WD3Z84
					More data for this Ligand-Target Pair