Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Sodium/bile acid cotransporter' and Ligand = 'BDBM400024'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/bile acid cotransporter (Homo sapiens (Human))	BDBM400024 (N-(3-chloro-4-fluorophenyl)-7-(2-((3,3-difluoro-1-...) Show SMILES CNC(=O)C1(CC(F)(F)C1)NC(=O)C(=O)c1c(C)c(C(=O)Nc2ccc(F)c(Cl)c2)n2CCCc12 Show InChI InChI=1S/C23H22ClF3N4O4/c1-11-16(18(32)20(34)30-22(21(35)28-2)9-23(26,27)10-22)15-4-3-7-31(15)17(11)19(33)29-12-5-6-14(25)13(24)8-12/h5-6,8H,3-4,7,9-10H2,1-2H3,(H,28,35)(H,29,33)(H,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	14.9	n/a	n/a	n/a	n/a
Celgene Quantical Research, Inc. US Patent									US Patent US9714230 (2017) BindingDB Entry DOI: 10.7270/Q2BR8X9J
					More data for this Ligand-Target Pair
Sodium/bile acid cotransporter (Homo sapiens (Human))	BDBM400024 (N-(3-chloro-4-fluorophenyl)-7-(2-((3,3-difluoro-1-...) Show SMILES CNC(=O)C1(CC(F)(F)C1)NC(=O)C(=O)c1c(C)c(C(=O)Nc2ccc(F)c(Cl)c2)n2CCCc12 Show InChI InChI=1S/C23H22ClF3N4O4/c1-11-16(18(32)20(34)30-22(21(35)28-2)9-23(26,27)10-22)15-4-3-7-31(15)17(11)19(33)29-12-5-6-14(25)13(24)8-12/h5-6,8H,3-4,7,9-10H2,1-2H3,(H,28,35)(H,29,33)(H,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	14.9	n/a	n/a	n/a	n/a
University of California at Los Angeles					Assay Description A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...				Bioorg Med Chem 17: 7174-85 (2009) BindingDB Entry DOI: 10.7270/Q28G8P1P
					More data for this Ligand-Target Pair