Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50315426 ((1S)-1,5-Anhydro-1-[5-(4-ethoxybenzyl)-2-methoxy-4...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Competitive inhibition of human SGLT2 expressed in CHO-K1 cells assessed as inhibition of [14C]-alpha-methylglucoside uptake | Bioorg Med Chem 24: 1937-80 (2016) Article DOI: 10.1016/j.bmc.2016.03.004 BindingDB Entry DOI: 10.7270/Q22B90WR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50315426 ((1S)-1,5-Anhydro-1-[5-(4-ethoxybenzyl)-2-methoxy-4...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptake | J Med Chem 53: 3247-61 (2010) Article DOI: 10.1021/jm901893x BindingDB Entry DOI: 10.7270/Q2KH0NG6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50315426 ((1S)-1,5-Anhydro-1-[5-(4-ethoxybenzyl)-2-methoxy-4...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Guangdong Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of SGLT2 (unknown origin) | Bioorg Med Chem 26: 3947-3952 (2018) Article DOI: 10.1016/j.bmc.2018.06.017 BindingDB Entry DOI: 10.7270/Q2P84FJN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50315426 ((1S)-1,5-Anhydro-1-[5-(4-ethoxybenzyl)-2-methoxy-4...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Jamia Hamdard Curated by ChEMBL | Assay Description Inhibition of human SGLT2 | Eur J Med Chem 184: (2019) Article DOI: 10.1016/j.ejmech.2019.111773 BindingDB Entry DOI: 10.7270/Q2TT4V97 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50315426 ((1S)-1,5-Anhydro-1-[5-(4-ethoxybenzyl)-2-methoxy-4...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Jamia Hamdard Curated by ChEMBL | Assay Description Inhibition OF SGLT2 (unknown origin) | Eur J Med Chem 184: (2019) Article DOI: 10.1016/j.ejmech.2019.111773 BindingDB Entry DOI: 10.7270/Q2TT4V97 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50315426 ((1S)-1,5-Anhydro-1-[5-(4-ethoxybenzyl)-2-methoxy-4...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a |
Terns Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of SGLT2 (unknown origin) | J Med Chem 63: 5031-5073 (2020) Article DOI: 10.1021/acs.jmedchem.9b01701 BindingDB Entry DOI: 10.7270/Q2DJ5JXG | |||||||||||
More data for this Ligand-Target Pair |