Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/hydrogen exchanger 1' and Ligand = 'BDBM50297576'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/hydrogen exchanger 1 (Rattus norvegicus)	BDBM50297576 (CHEMBL561142 | N''-[2-(1H-benzimidazol-2-ylthio)-5...) Show SMILES COc1cc2CC(Sc3nc4ccccc4[nH]3)C(=NN=C(N)N)c2cc1OC |w:18.20,(28.87,-5.3,;30.2,-4.53,;30.2,-2.98,;28.87,-2.21,;28.87,-.68,;27.73,.34,;28.35,1.74,;27.58,3.08,;26.04,3.08,;25.13,4.34,;23.65,3.85,;22.3,4.62,;20.98,3.85,;20.98,2.3,;22.31,1.53,;23.65,2.3,;25.13,1.82,;29.88,1.59,;30.91,2.74,;32.42,2.42,;33.45,3.57,;34.96,3.26,;32.97,5.04,;30.21,.08,;31.53,-.68,;31.54,-2.21,;32.87,-2.98,;32.88,-4.52,)| Show InChI InChI=1S/C19H20N6O2S/c1-26-14-7-10-8-16(28-19-22-12-5-3-4-6-13(12)23-19)17(24-25-18(20)21)11(10)9-15(14)27-2/h3-7,9,16H,8H2,1-2H3,(H,22,23)(H4,20,21,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11.2	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assay				Eur J Med Chem 44: 3771-6 (2009) Article DOI: 10.1016/j.ejmech.2009.04.036 BindingDB Entry DOI: 10.7270/Q2474BS7
					More data for this Ligand-Target Pair