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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Sodium/hydrogen exchanger 1 | ||
| Ligand | BDBM50297576 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_583577 (CHEMBL1059092) | ||
| IC50 | 11.2±n/a nM | ||
| Citation |  Zhang, R; Dong, J; Xu, YG; Hua, WY; Wen, N; You, QD Synthesis and bioactivity of substituted indan-1-ylideneaminoguanidine derivatives. Eur J Med Chem44:3771-6 (2009) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Sodium/hydrogen exchanger 1 | |||
| Name: | Sodium/hydrogen exchanger 1 | ||
| Synonyms: | NHE-1 | Na(+)/H(+) exchanger 1 | Nhe1 | SL9A1_RAT | Slc9a1 | Solute carrier family 9 member 1 | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 91655.00 | ||
| Organism: | Rattus norvegicus | ||
| Description: | ChEMBL_862370 | ||
| Residue: | 820 | ||
| Sequence: |
| ||
| BDBM50297576 | |||
| n/a | |||
| Name | BDBM50297576 | ||
| Synonyms: | CHEMBL561142 | N''-[2-(1H-benzimidazol-2-ylthio)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-ylidene]carbonohydrazonic diamide dihydrochloride | ||
| Type | Small organic molecule | ||
| Emp. Form. | C19H20N6O2S | ||
| Mol. Mass. | 396.466 | ||
| SMILES | COc1cc2CC(Sc3nc4ccccc4[nH]3)C(=NN=C(N)N)c2cc1OC |w:18.20,(28.87,-5.3,;30.2,-4.53,;30.2,-2.98,;28.87,-2.21,;28.87,-.68,;27.73,.34,;28.35,1.74,;27.58,3.08,;26.04,3.08,;25.13,4.34,;23.65,3.85,;22.3,4.62,;20.98,3.85,;20.98,2.3,;22.31,1.53,;23.65,2.3,;25.13,1.82,;29.88,1.59,;30.91,2.74,;32.42,2.42,;33.45,3.57,;34.96,3.26,;32.97,5.04,;30.21,.08,;31.53,-.68,;31.54,-2.21,;32.87,-2.98,;32.88,-4.52,)| | ||
| Structure | 
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