Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium channel protein type 4 subunit alpha (Homo sapiens (Human)) | BDBM190233 (US9174999, Table 1, Compound 1) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00378 BindingDB Entry DOI: 10.7270/Q2SF3151 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 4 subunit alpha (Rattus norvegicus (Rat)) | BDBM190233 (US9174999, Table 1, Compound 1) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
The Board of Trustees of the Leland Stanford Junior University US Patent | Assay Description In initial studies, we designed a set of molecules with branching at the nitrogen of the carbamate side chain as well as the carbon adjacent to the n... | US Patent US9174999 (2015) BindingDB Entry DOI: 10.7270/Q2C24V68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 4 subunit alpha (Homo sapiens (Human)) | BDBM190233 (US9174999, Table 1, Compound 1) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
SiteOne Therapeutics Curated by ChEMBL | Assay Description Inhibition of human Nav1.4 expressed in HEK293 cells by electrophysiology assay | J Med Chem 62: 8695-8710 (2019) Article DOI: 10.1021/acs.jmedchem.8b01906 BindingDB Entry DOI: 10.7270/Q2M90CZD | |||||||||||
More data for this Ligand-Target Pair |