BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 9 subunit alpha' and Ligand = 'BDBM50223136'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50223136 (CHEMBL249360 \| N-((R)-1-((R)-7-chloro-1-isopropyl-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human NaV1.7 channel expressed in HEK293 cells by FRET assay				Bioorg Med Chem Lett 23: 3640-5 (2013) Article DOI: 10.1016/j.bmcl.2013.03.121 BindingDB Entry DOI: 10.7270/Q2W098VM
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50223136 (CHEMBL249360 \| N-((R)-1-((R)-7-chloro-1-isopropyl-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human sodium channel Nav1.7 by FRET assay				Bioorg Med Chem Lett 17: 6172-7 (2007) Article DOI: 10.1016/j.bmcl.2007.09.032 BindingDB Entry DOI: 10.7270/Q2X92B00
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair