Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent glycine transporter 1' and Ligand = 'BDBM201153'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM201153 (US9233953, 114) Show SMILES FC(F)c1nc(no1)N1CCN(C(C1)c1ccc(F)cc1)C(=O)C1CCS(=O)(=O)CC1 Show InChI InChI=1S/C19H21F3N4O4S/c20-14-3-1-12(2-4-14)15-11-25(19-23-17(16(21)22)30-24-19)7-8-26(15)18(27)13-5-9-31(28,29)10-6-13/h1-4,13,15-16H,5-11H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Cells expressing either endogenously the GlyT1 transporter like JAR cells (human placental choriocarcinoma cells; e.g. WO 2008/002583) or SK-N-MC cel...				US Patent US9233953 (2016) BindingDB Entry DOI: 10.7270/Q2Q81BVM
					More data for this Ligand-Target Pair