Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent glycine transporter 2' and Ligand = 'BDBM50335012'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 2 (Rattus norvegicus)	BDBM50335012 (3-Biphenyl-4-yl-5-methyl-4-(2-methylphenyl)-4H-1,2...) Show SMILES Cc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1ccccc1C |(32.05,-21.71,;30.58,-21.23,;30.11,-19.76,;28.57,-19.76,;28.09,-21.22,;26.77,-22,;26.77,-23.54,;25.44,-24.32,;24.11,-23.55,;24.1,-22.02,;25.42,-21.24,;22.78,-24.32,;21.45,-23.56,;20.12,-24.33,;20.12,-25.87,;21.45,-26.64,;22.79,-25.87,;29.34,-22.13,;29.34,-23.66,;28,-24.43,;28,-25.97,;29.33,-26.74,;30.67,-25.97,;30.66,-24.43,;32,-23.66,)| Show InChI InChI=1S/C22H19N3/c1-16-8-6-7-11-21(16)25-17(2)23-24-22(25)20-14-12-19(13-15-20)18-9-4-3-5-10-18/h3-15H,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cells				J Med Chem 54: 387-91 (2011) Article DOI: 10.1021/jm101031u BindingDB Entry DOI: 10.7270/Q2H9965H
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