BindingDB PrimarySearch

Found 48 hits Enz. Inhib. hit(s) with Target = 'Sodium-dependent dopamine transporter' and Ligand = 'BDBM50005536'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	Article PubMed	11.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research Foundation Curated by PDSP K_i Database									Psychopharmacology (Berl) 124: 57-73 (1996) Article DOI: 10.1007/bf02245606 BindingDB Entry DOI: 10.7270/Q2610XV6
Janssen Research Foundation Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INSERM U316 Curated by PDSP K_i Database									J Pharmacol Exp Ther 282: 467-74 (1997) BindingDB Entry DOI: 10.7270/Q2X928VC
INSERM U316 Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University Curated by PDSP K_i Database									J Pharmacol Exp Ther 314: 575-83 (2005) Article DOI: 10.1124/jpet.105.085829 BindingDB Entry DOI: 10.7270/Q27M06H6
Duquesne University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PubMed	14.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by PDSP K_i Database									J Pharmacol Exp Ther 293: 686-96 (2000) BindingDB Entry DOI: 10.7270/Q2H993QF
Wake Forest University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	15.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by PDSP K_i Database									Mol Pharmacol 45: 125-35 (1994) BindingDB Entry DOI: 10.7270/Q2NG4P5C
University of Toronto Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by PDSP K_i Database									J Pharmacol Exp Ther 318: 657-65 (2006) Article DOI: 10.1124/jpet.106.103382 BindingDB Entry DOI: 10.7270/Q2SF2TRS
Wyeth Research Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	22.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428 binding to human recombinant DAT expressed in CHO cells by scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	22.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research& Development Curated by ChEMBL					Assay Description Displacement of [3H]WIN35428 from human recombinant DAT expressed in CHO cells				J Med Chem 53: 4511-21 (2010) Article DOI: 10.1021/jm100053t BindingDB Entry DOI: 10.7270/Q2PC32JR
Pfizer Global Research& Development Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	22.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-WIN-35428 from human DAT expressed in CHO cells				J Med Chem 54: 6824-31 (2011) Article DOI: 10.1021/jm200733r BindingDB Entry DOI: 10.7270/Q2XD1227
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	22.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by PDSP K_i Database									Mol Pharmacol 45: 125-35 (1994) BindingDB Entry DOI: 10.7270/Q2NG4P5C
University of Toronto Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by PDSP K_i Database									Mol Pharmacol 45: 125-35 (1994) BindingDB Entry DOI: 10.7270/Q2NG4P5C
University of Toronto Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	Article PubMed	25.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NIH Curated by PDSP K_i Database									Synapse 39: 32-41 (2001) Article DOI: 10.1002/1098-2396(20010101)39:1 BindingDB Entry DOI: 10.7270/Q2NV9GT3
NIH Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PubMed	28.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by PDSP K_i Database									J Pharmacol Exp Ther 293: 686-96 (2000) BindingDB Entry DOI: 10.7270/Q2H993QF
Wake Forest University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	Article PubMed	29.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Industri A/S Curated by PDSP K_i Database									Eur J Pharmacol 166: 493-504 (1989) Article DOI: 10.1016/0014-2999(89)90363-4 BindingDB Entry DOI: 10.7270/Q28C9TR3
Novo Industri A/S Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University Curated by PDSP K_i Database									J Pharmacol Exp Ther 314: 575-83 (2005) Article DOI: 10.1124/jpet.105.085829 BindingDB Entry DOI: 10.7270/Q27M06H6
Duquesne University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Medical Center at Knoxville 37920. Curated by ChEMBL					Assay Description Inhibitory constant towards reuptake of [125I]-12 from dopamine transporter in rat striatal membranes				J Med Chem 37: 1535-42 (1994) BindingDB Entry DOI: 10.7270/Q2SX6DVH
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Inhibition of [125I]RTI-55 binding to recombinant human DAT expressed in HEK293 cell membranes preincubated for 10 mins followed by radioligand addit...				J Med Chem 60: 3109-3123 (2017) Article DOI: 10.1021/acs.jmedchem.7b00141 BindingDB Entry DOI: 10.7270/Q2Z60RBZ
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Medical Center at Knoxville 37920. Curated by ChEMBL					Assay Description Inhibitory constant towards reuptake of [125I]-13 from dopamine transporter in rat striatal membranes				J Med Chem 37: 1535-42 (1994) BindingDB Entry DOI: 10.7270/Q2SX6DVH
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	Article PubMed	44.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
FAES FARMA S A Curated by ChEMBL					Assay Description Binding affinity against dopamine transporter (DAT) by displacement of [3H]WIN-35428 in male wistar rats				J Med Chem 46: 5512-32 (2003) Article DOI: 10.1021/jm0309349 BindingDB Entry DOI: 10.7270/Q2QF8TMN
FAES FARMA S A Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Drew University Curated by ChEMBL					Assay Description Displacement of [125I]- RTI-55 from Dopamine transporter expressed in HEK cells				J Med Chem 45: 4097-109 (2002) BindingDB Entry DOI: 10.7270/Q2MC90R8
Drew University Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Drew University Curated by ChEMBL					Assay Description Inhibition of [125I]- RTI -55 binding at the Dopamine transporter sites on HEK-hDAT cells				J Med Chem 45: 4110-8 (2002) BindingDB Entry DOI: 10.7270/Q25Q4VF3
Drew University Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INSERM U316 Curated by PDSP K_i Database									J Pharmacol Exp Ther 282: 467-74 (1997) BindingDB Entry DOI: 10.7270/Q2X928VC
INSERM U316 Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by PDSP K_i Database									Mol Pharmacol 45: 125-35 (1994) BindingDB Entry DOI: 10.7270/Q2NG4P5C
University of Toronto Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PubMed	63.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by PDSP K_i Database									J Pharmacol Exp Ther 293: 686-96 (2000) BindingDB Entry DOI: 10.7270/Q2H993QF
Wake Forest University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	74	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Compound tested in vitro for inhibition of translation using highly active Escherichia coli S30 and a plasmid containing a gene expressing truncated ...				J Med Chem 60: 3109-3123 (2017) Article DOI: 10.1021/acs.jmedchem.7b00141 BindingDB Entry DOI: 10.7270/Q2Z60RBZ
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (MOUSE)	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	Article PubMed	404	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Inhibit of purified bovine Farnesyl protein transferase.				J Med Chem 60: 3109-3123 (2017) Article DOI: 10.1021/acs.jmedchem.7b00141 BindingDB Entry DOI: 10.7270/Q2Z60RBZ
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]GBR-12935 binding to the dopamine transporter.				J Med Chem 35: 969-81 (1992) BindingDB Entry DOI: 10.7270/Q24T6K0F
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	8.10	n/a	n/a	n/a	n/a	n/a	n/a
Drew University Curated by ChEMBL					Assay Description Ability to displace [3H]WIN-35428 from Dopamine Transporter of rat striatal membrane				J Med Chem 45: 4097-109 (2002) BindingDB Entry DOI: 10.7270/Q2MC90R8
Drew University Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	8.10	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse-Intramural Research Program/NIH Curated by ChEMBL					Assay Description Ability to displace [3H]-WIN-35,428 from dopamine transporter in rat caudate putamen tissue				J Med Chem 45: 4119-27 (2002) BindingDB Entry DOI: 10.7270/Q21Z43R6
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	8.10	n/a	n/a	n/a	n/a	n/a	n/a
Drew University Curated by ChEMBL					Assay Description Inhibition of [3H]-WIN- 35,428 binding to the dopamine transporter in rat brain				J Med Chem 39: 4935-41 (1997) Article DOI: 10.1021/jm960288w BindingDB Entry DOI: 10.7270/Q2ZK5FSR
Drew University Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	8.40	n/a	n/a	n/a	n/a	n/a	n/a
Drew University Curated by ChEMBL					Assay Description Inhibition of [3H]-dopamine uptake at the dopamine transporter in rat striatal tissue				J Med Chem 39: 4935-41 (1997) Article DOI: 10.1021/jm960288w BindingDB Entry DOI: 10.7270/Q2ZK5FSR
Drew University Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]cocaine binding to the dopamine transporter.				J Med Chem 35: 969-81 (1992) BindingDB Entry DOI: 10.7270/Q24T6K0F
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	12.9	n/a	n/a	n/a	n/a	n/a	n/a
Drew University Curated by ChEMBL					Assay Description Ability to displace [3H]- WIN 35,428 from dopamine transporter on rat striatal membrane.				J Med Chem 45: 4110-8 (2002) BindingDB Entry DOI: 10.7270/Q25Q4VF3
Drew University Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Inhibition of recombinant human DAT expressed in HEK293 cell membranes assessed as reduction in [3H]-DA uptake incubated for 22 mins by micro beta sc...				J Med Chem 60: 3109-3123 (2017) Article DOI: 10.1021/acs.jmedchem.7b00141 BindingDB Entry DOI: 10.7270/Q2Z60RBZ
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]BTCP binding to the dopamine transporter.				J Med Chem 35: 969-81 (1992) BindingDB Entry DOI: 10.7270/Q24T6K0F
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (MOUSE)	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Inhibition of mouse DAT expressed in HEK293 cells assessed as reduction in [3H]-DA uptake				J Med Chem 60: 3109-3123 (2017) Article DOI: 10.1021/acs.jmedchem.7b00141 BindingDB Entry DOI: 10.7270/Q2Z60RBZ
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]GBR-12935 binding to the dopamine transporter.				J Med Chem 35: 969-81 (1992) BindingDB Entry DOI: 10.7270/Q24T6K0F
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428 binding to human recombinant DAT expressed in CHO cells				Bioorg Med Chem Lett 19: 2464-7 (2009) Article DOI: 10.1016/j.bmcl.2009.03.054 BindingDB Entry DOI: 10.7270/Q2T43V1C
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	22.1	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]WIN-35428 from human recombinant DAT expressed in CHO cells				Bioorg Med Chem Lett 18: 6067-70 (2008) Article DOI: 10.1016/j.bmcl.2008.10.026 BindingDB Entry DOI: 10.7270/Q2JD4XQT
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	22.1	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]WIN-35428 form human DAT expressed in CHO cell membranes				Bioorg Med Chem Lett 20: 2809-12 (2010) Article DOI: 10.1016/j.bmcl.2010.03.059 BindingDB Entry DOI: 10.7270/Q2028RQV
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	n/a	n/a	42.6	n/a	n/a	n/a	n/a	n/a	n/a
Drew University Curated by ChEMBL					Assay Description Ability to displace [3H]WIN-35428 from Dopamine Transporter in guinea pig striatal membrane				J Med Chem 45: 4097-109 (2002) BindingDB Entry DOI: 10.7270/Q2MC90R8
Drew University Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	n/a	n/a	42.6	n/a	n/a	n/a	n/a	n/a	n/a
Drew University Curated by ChEMBL					Assay Description Ability to displace [3H]- WIN 35,428 from dopamine transporter on guinea pig striatal membrane.				J Med Chem 45: 4110-8 (2002) BindingDB Entry DOI: 10.7270/Q25Q4VF3
Drew University Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	42.6	n/a	n/a	n/a	n/a	n/a	n/a
Drew University Curated by ChEMBL					Assay Description Compound was tested for inhibition of [3H]-WIN- 35,428 binding at the dopamine transporter in rat striatal membrane				J Med Chem 39: 4935-41 (1997) Article DOI: 10.1021/jm960288w BindingDB Entry DOI: 10.7270/Q2ZK5FSR
Drew University Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Drew University Curated by ChEMBL					Assay Description Inhibition of dopamine uptake in HEK cells expressing human dopamine transporter (hDAT)				J Med Chem 45: 4097-109 (2002) BindingDB Entry DOI: 10.7270/Q2MC90R8
Drew University Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]GBR-12935 binding to the dopamine transporter.				J Med Chem 35: 969-81 (1992) BindingDB Entry DOI: 10.7270/Q24T6K0F
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]dopamine uptake at the dopamine transporter.				J Med Chem 35: 969-81 (1992) BindingDB Entry DOI: 10.7270/Q24T6K0F
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35065-2 binding to the dopamine transporter.				J Med Chem 35: 969-81 (1992) BindingDB Entry DOI: 10.7270/Q24T6K0F
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	n/a	8.60	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Binding affinity to a single, sodium-dependent site on the Dopamine transporter in rat striatal membranes				Bioorg Med Chem Lett 10: 1443-6 (2000) BindingDB Entry DOI: 10.7270/Q2CZ37PP
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair