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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium-dependent noradrenaline transporter' and Ligand = 'BDBM50294277'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium-dependent noradrenaline transporter


(Homo sapiens (Human))		BDBM50294277
PNG
(CHEMBL560049 | rac-3-(piperidin-4-yl(2,3,5-trichlo...)
Show SMILES Clc1cc(Cl)c(Cl)c(OC(C2CCNCC2)c2cccnc2)c1
Show InChI InChI=1S/C17H17Cl3N2O/c18-13-8-14(19)16(20)15(9-13)23-17(11-3-6-21-7-4-11)12-2-1-5-22-10-12/h1-2,5,8-11,17,21H,3-4,6-7H2
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n/an/a 215n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of [3H]NA uptake at human NET expressed in HEK293 cells

Bioorg Med Chem Lett 19: 2829-34 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.090
BindingDB Entry DOI: 10.7270/Q2HX1CQX
More data for this
Ligand-Target Pair