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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Somatostatin receptor type 5' and Ligand = 'BDBM50322977'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Somatostatin receptor type 5


(Homo sapiens (Human))		BDBM50322977
PNG
(CHEMBL1210268 | N-(1-(3,5-diethoxy-4-fluorobenzyl)...)
Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2ccc(NC)nc2)cc(OCC)c1F
Show InChI InChI=1S/C23H31FN4O3/c1-4-30-19-12-16(13-20(22(19)24)31-5-2)15-28-10-8-18(9-11-28)27-23(29)17-6-7-21(25-3)26-14-17/h6-7,12-14,18H,4-5,8-11,15H2,1-3H3,(H,25,26)(H,27,29)
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PC cid
PC sid
UniChem

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Article
PubMed
 18n/an/an/an/an/an/an/an/a



F. Hoffmann-La Roche Ltd

Curated by ChEMBL


Assay Description
Displacement of radio labeled 11 Tyr SST14 from human SST5 receptor expressed in CHO cells

Bioorg Med Chem Lett 20: 4521-5 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.026
BindingDB Entry DOI: 10.7270/Q2J103BN
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))		BDBM50322977
PNG
(CHEMBL1210268 | N-(1-(3,5-diethoxy-4-fluorobenzyl)...)
Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2ccc(NC)nc2)cc(OCC)c1F
Show InChI InChI=1S/C23H31FN4O3/c1-4-30-19-12-16(13-20(22(19)24)31-5-2)15-28-10-8-18(9-11-28)27-23(29)17-6-7-21(25-3)26-14-17/h6-7,12-14,18H,4-5,8-11,15H2,1-3H3,(H,25,26)(H,27,29)
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KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a>1.00E+3n/an/an/an/a



F. Hoffmann-La Roche Ltd

Curated by ChEMBL


Assay Description
Antagonist activity at human SST5 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation by FRET assay

Bioorg Med Chem Lett 20: 4521-5 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.026
BindingDB Entry DOI: 10.7270/Q2J103BN
More data for this
Ligand-Target Pair