BindingDB PrimarySearch

Found 8 hits Enz. Inhib. hit(s) with Target = 'Substance-K receptor' and Ligand = 'BDBM50071484'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Substance-K receptor (Rattus norvegicus (Rat))	BDBM50071484 (CHEMBL308148 \| N-[(R)-4-(4-Acetylamino-4-phenyl-pi...) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [125I]-NKA binding to neurokinin NK2 receptor from rat duodenum membranes				Bioorg Med Chem Lett 3: 925-930 (1993) Article DOI: 10.1016/S0960-894X(00)80694-0 BindingDB Entry DOI: 10.7270/Q2N29WW1
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-K receptor (Bos taurus)	BDBM50071484 (CHEMBL308148 \| N-[(R)-4-(4-Acetylamino-4-phenyl-pi...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
St. John's University Curated by ChEMBL					Assay Description Binding affinity against bovine Tachykinin receptor 2				Bioorg Med Chem Lett 14: 4779-82 (2004) Article DOI: 10.1016/j.bmcl.2004.06.053 BindingDB Entry DOI: 10.7270/Q2VH5PKB
St. John's University Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-K receptor (Homo sapiens (Human))	BDBM50071484 (CHEMBL308148 \| N-[(R)-4-(4-Acetylamino-4-phenyl-pi...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity towards Tachykinin receptor 2 in CHO cells using [3H]-neurokinin A as radioligand				Bioorg Med Chem Lett 10: 2329-32 (2001) BindingDB Entry DOI: 10.7270/Q21Z43P9
Schering-Plough Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-K receptor (HAMSTER)	BDBM50071484 (CHEMBL308148 \| N-[(R)-4-(4-Acetylamino-4-phenyl-pi...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description The compound was evaluated for the inhibition of [125I]-NKA binding to neurokinin NK2 receptor from hamster urinary bladder membranes				Bioorg Med Chem Lett 3: 925-930 (1993) Article DOI: 10.1016/S0960-894X(00)80694-0 BindingDB Entry DOI: 10.7270/Q2N29WW1
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-K receptor (Rattus norvegicus (Rat))	BDBM50071484 (CHEMBL308148 \| N-[(R)-4-(4-Acetylamino-4-phenyl-pi...) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article	945	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description The compound was evaluated for the inhibition of [125I]-NKA binding to Tachykinin receptor 2 from rat duodenum membranes				Bioorg Med Chem Lett 3: 925-930 (1993) Article DOI: 10.1016/S0960-894X(00)80694-0 BindingDB Entry DOI: 10.7270/Q2N29WW1
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-K receptor (Homo sapiens (Human))	BDBM50071484 (CHEMBL308148 \| N-[(R)-4-(4-Acetylamino-4-phenyl-pi...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.130	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of cloned human NK2 (Neurokinin 2) receptor, stably expressed in chinese hamster ovary (CHO) cells was determined				Bioorg Med Chem Lett 8: 2259-62 (1999) BindingDB Entry DOI: 10.7270/Q2Z31XTN
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-K receptor (Homo sapiens (Human))	BDBM50071484 (CHEMBL308148 \| N-[(R)-4-(4-Acetylamino-4-phenyl-pi...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	0.440	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against human NK2 receptors from HSKR-1 cells using [125I]-Iodohistidyl NKA				Bioorg Med Chem Lett 6: 951-956 (1996) Article DOI: 10.1016/0960-894X(96)00148-5 BindingDB Entry DOI: 10.7270/Q2GM8794
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-K receptor (Homo sapiens (Human))	BDBM50071484 (CHEMBL308148 \| N-[(R)-4-(4-Acetylamino-4-phenyl-pi...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity was determined against human NK2 receptor in CHO cells using [125I]-neurokinin A as radioligand				Bioorg Med Chem Lett 6: 605-608 (1996) Article DOI: 10.1016/0960-894X(96)00075-3 BindingDB Entry DOI: 10.7270/Q2B27V80
TBA Curated by ChEMBL					More data for this Ligand-Target Pair