Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'TGF-beta receptor type-1' and Ligand = 'BDBM50151361'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50151361 (5-(naphthalen-1-yl)-4-(pyridin-2-yl)thiazol-2-amin...) Show SMILES Nc1nc(c(s1)-c1cccc2ccccc12)-c1ccccn1 Show InChI InChI=1S/C18H13N3S/c19-18-21-16(15-10-3-4-11-20-15)17(22-18)14-9-5-7-12-6-1-2-8-13(12)14/h1-11H,(H2,19,21)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Stimulation of Transforming growth factor beta receptor I kinase in HepG2 cells				J Med Chem 47: 4494-506 (2004) Article DOI: 10.1021/jm0400247 BindingDB Entry DOI: 10.7270/Q2VQ325T
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50151361 (5-(naphthalen-1-yl)-4-(pyridin-2-yl)thiazol-2-amin...) Show SMILES Nc1nc(c(s1)-c1cccc2ccccc12)-c1ccccn1 Show InChI InChI=1S/C18H13N3S/c19-18-21-16(15-10-3-4-11-20-15)17(22-18)14-9-5-7-12-6-1-2-8-13(12)14/h1-11H,(H2,19,21)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity to Activin A receptor type II-like kinase (ALK5) in fluorescence polarization binding assay; Range is (5.326-22.574)				J Med Chem 47: 4494-506 (2004) Article DOI: 10.1021/jm0400247 BindingDB Entry DOI: 10.7270/Q2VQ325T
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50151361 (5-(naphthalen-1-yl)-4-(pyridin-2-yl)thiazol-2-amin...) Show SMILES Nc1nc(c(s1)-c1cccc2ccccc12)-c1ccccn1 Show InChI InChI=1S/C18H13N3S/c19-18-21-16(15-10-3-4-11-20-15)17(22-18)14-9-5-7-12-6-1-2-8-13(12)14/h1-11H,(H2,19,21)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of TGFR1				Eur J Med Chem 44: 4259-65 (2009) Article DOI: 10.1016/j.ejmech.2009.07.008 BindingDB Entry DOI: 10.7270/Q2BC3ZM9
					More data for this Ligand-Target Pair