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Found 1 hit Enz. Inhib. hit(s) with Target = 'Thromboxane-A synthase' and Ligand = 'BDBM50024951'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Thromboxane-A synthase


(Rattus norvegicus)		BDBM50024951
PNG
(3-(4-Imidazol-1-yl-butyl)-8-trifluoromethyl-1H-qui...)
Show SMILES FC(F)(F)c1cccc2c1[nH]c(=O)n(CCCCn1ccnc1)c2=O
Show InChI InChI=1S/C16H15F3N4O2/c17-16(18,19)12-5-3-4-11-13(12)21-15(25)23(14(11)24)8-2-1-7-22-9-6-20-10-22/h3-6,9-10H,1-2,7-8H2,(H,21,25)
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PC cid
PC sid
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Similars
PubMed
n/an/a 50n/an/an/an/an/an/a



Medical Research Division of American Cyanamid Company

Curated by ChEMBL


Assay Description
Tested for inhibition of thromboxane synthetase from spontaneously hypertensive rats

J Med Chem 30: 2277-83 (1988)


BindingDB Entry DOI: 10.7270/Q23T9HT6
More data for this
Ligand-Target Pair