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Found 1 hit Enz. Inhib. hit(s) with Target = 'Thromboxane-A synthase' and Ligand = 'BDBM50026531'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Thromboxane-A synthase


(Homo sapiens (Human))		BDBM50026531
PNG
(2,2-Dimethyl-7-pyridin-3-yl-7-thiophen-2-yl-hept-6...)
Show SMILES CC(C)(CCC\C=C(/c1cccs1)c1cccnc1)C(O)=O
Show InChI InChI=1S/C18H21NO2S/c1-18(2,17(20)21)10-4-3-8-15(16-9-6-12-22-16)14-7-5-11-19-13-14/h5-9,11-13H,3-4,10H2,1-2H3,(H,20,21)/b15-8-
KEGG

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PC sid
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Similars
PubMed
n/an/a 18n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomes

J Med Chem 28: 287-94 (1985)


BindingDB Entry DOI: 10.7270/Q2P26ZPB
More data for this
Ligand-Target Pair