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Found 1 hit Enz. Inhib. hit(s) with Target = 'Thromboxane-A synthase' and Ligand = 'BDBM50026538'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Thromboxane-A synthase


(Homo sapiens (Human))		BDBM50026538
PNG
(7-Naphthalen-2-yl-7-pyridin-3-yl-hept-6-enoic acid...)
Show SMILES OC(=O)CCCC\C=C(\c1cccnc1)c1ccc2ccccc2c1
Show InChI InChI=1S/C22H21NO2/c24-22(25)11-3-1-2-10-21(20-9-6-14-23-16-20)19-13-12-17-7-4-5-8-18(17)15-19/h4-10,12-16H,1-3,11H2,(H,24,25)/b21-10+
KEGG

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PC cid
PC sid
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Similars
PubMed
n/an/a 19n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomes

J Med Chem 28: 287-94 (1985)


BindingDB Entry DOI: 10.7270/Q2P26ZPB
More data for this
Ligand-Target Pair