BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Thromboxane-A synthase' and Ligand = 'BDBM50034744'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Thromboxane-A synthase


(Homo sapiens (Human))		BDBM50034744
PNG
(3-(6-{4-[(2S,4S,5R)-5-((Z)-5-Carboxy-pent-2-enyl)-...)
Show SMILES OC(=O)CC\C=C/C[C@@H]1CO[C@@H](O[C@@H]1c1ccccc1O)c1ccc(OCCCCCCOc2cc(ccc2OCCn2ccnc2)C(O)=O)cc1
Show InChI InChI=1S/C40H46N2O10/c43-34-12-7-6-11-33(34)38-31(10-4-3-5-13-37(44)45)27-51-40(52-38)29-14-17-32(18-15-29)48-23-8-1-2-9-24-49-36-26-30(39(46)47)16-19-35(36)50-25-22-42-21-20-41-28-42/h3-4,6-7,11-12,14-21,26,28,31,38,40,43H,1-2,5,8-10,13,22-25,27H2,(H,44,45)(H,46,47)/b4-3-/t31-,38+,40+/m1/s1
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 40n/an/an/an/an/an/a



ZENECA Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human microsomal thromboxane synthase.

J Med Chem 38: 1608-28 (1995)


BindingDB Entry DOI: 10.7270/Q2319TWW
More data for this
Ligand-Target Pair