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Found 1 hit Enz. Inhib. hit(s) with Target = 'Thromboxane-A synthase' and Ligand = 'BDBM50037046'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Thromboxane-A synthase


(Rattus norvegicus)		BDBM50037046
PNG
(2-Amino-5-methoxy-7-methyl-4-pyridin-3-ylmethyl-be...)
Show SMILES COc1c(O)c(C)c2sc(N)nc2c1Cc1cccnc1
Show InChI InChI=1S/C15H15N3O2S/c1-8-12(19)13(20-2)10(6-9-4-3-5-17-7-9)11-14(8)21-15(16)18-11/h3-5,7,19H,6H2,1-2H3,(H2,16,18)
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PubMed
n/an/a 110n/an/an/an/an/an/a



Eisai Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of rat

J Med Chem 37: 3062-70 (1994)


BindingDB Entry DOI: 10.7270/Q2WM1F2J
More data for this
Ligand-Target Pair