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Found 1 hit Enz. Inhib. hit(s) with Target = 'Thromboxane-A synthase' and Ligand = 'BDBM50037767'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Thromboxane-A synthase


(Rattus norvegicus)		BDBM50037767
PNG
(5-[1-(4-Bromo-phenyl)-2-imidazol-1-yl-3-phenyl-pro...)
Show SMILES OC(=O)CCCCO\N=C(\C(Cc1ccccc1)n1ccnc1)c1ccc(Br)cc1
Show InChI InChI=1S/C23H24BrN3O3/c24-20-11-9-19(10-12-20)23(26-30-15-5-4-8-22(28)29)21(27-14-13-25-17-27)16-18-6-2-1-3-7-18/h1-3,6-7,9-14,17,21H,4-5,8,15-16H2,(H,28,29)/b26-23+
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PC cid
PC sid
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PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Pharmacia-Farmitalia Carlo Erba

Curated by ChEMBL


Assay Description
In vitro inhibition of thromboxane-A2 synthase in rat whole blood during clotting at 37 degrees centigrade

J Med Chem 37: 3588-604 (1994)


BindingDB Entry DOI: 10.7270/Q2C24VFD
More data for this
Ligand-Target Pair