Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50071142 ((E)-7-[4-(4-Benzylcarbamoyl-oxazol-2-yl)-phenyl]-7...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 24.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro for inhibitory activity against thromboxane synthase | J Med Chem 41: 5362-74 (1999) Article DOI: 10.1021/jm980173n BindingDB Entry DOI: 10.7270/Q2V123Z8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50071142 ((E)-7-[4-(4-Benzylcarbamoyl-oxazol-2-yl)-phenyl]-7...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro inhibition of thromboxane synthase (TSI) activity was determined by using human serum levels of TXB2 | Bioorg Med Chem Lett 8: 1943-8 (1999) BindingDB Entry DOI: 10.7270/Q2DB8107 | |||||||||||
More data for this Ligand-Target Pair |