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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Thyroid hormone receptor alpha (Homo sapiens (Human)) | BDBM18886 (3-{3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)-5-[(E)...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | Purchase MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 36 | n/a | 32 | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. EC50 is the concentration of compound required to ... | J Med Chem 49: 6635-7 (2006) Article DOI: 10.1021/jm060521i BindingDB Entry DOI: 10.7270/Q23B5XDF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thyroid hormone receptor alpha (Homo sapiens (Human)) | BDBM18886 (3-{3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)-5-[(E)...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 36 | n/a | n/a | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. | Bioorg Med Chem Lett 17: 2018-21 (2007) Article DOI: 10.1016/j.bmcl.2007.01.009 BindingDB Entry DOI: 10.7270/Q2R20ZMS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
