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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Transcription factor 7-like 2' and Ligand = 'BDBM50489463'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transcription factor 7-like 2


(Homo sapiens (Human))
BDBM50489463
PNG
(CHEMBL2323031)
Show SMILES OC(=O)c1cccc(NC(=O)C(=O)N\N=C2/C(=O)N(CC=C)c3ccccc23)c1
Show InChI InChI=1S/C20H16N4O5/c1-2-10-24-15-9-4-3-8-14(15)16(19(24)27)22-23-18(26)17(25)21-13-7-5-6-12(11-13)20(28)29/h2-9,11H,1,10H2,(H,21,25)(H,23,26)(H,28,29)/b22-16-
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PC cid
PC sid
UniChem
Article
PubMed
1.60E+4n/an/an/an/an/an/an/an/a



University of Utah

Curated by ChEMBL


Assay Description
Inhibition of human beta-casein/Tcf4 interaction after 1 hr by fluorescence polarization assay


ACS Med Chem Lett 4: 306-11 (2013)


Article DOI: 10.1021/ml300367f
BindingDB Entry DOI: 10.7270/Q2CN76TG
More data for this
Ligand-Target Pair
Transcription factor 7-like 2


(Homo sapiens (Human))
BDBM50489463
PNG
(CHEMBL2323031)
Show SMILES OC(=O)c1cccc(NC(=O)C(=O)N\N=C2/C(=O)N(CC=C)c3ccccc23)c1
Show InChI InChI=1S/C20H16N4O5/c1-2-10-24-15-9-4-3-8-14(15)16(19(24)27)22-23-18(26)17(25)21-13-7-5-6-12(11-13)20(28)29/h2-9,11H,1,10H2,(H,21,25)(H,23,26)(H,28,29)/b22-16-
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
Article
PubMed
2.10E+4n/an/an/an/an/an/an/an/a



University of Utah

Curated by ChEMBL


Assay Description
Inhibition of human beta-casein/Tcf4 interaction after 1 hr by alphascreen assay


ACS Med Chem Lett 4: 306-11 (2013)


Article DOI: 10.1021/ml300367f
BindingDB Entry DOI: 10.7270/Q2CN76TG
More data for this
Ligand-Target Pair