BindingDB logo
myBDB logout

null

SMILES: OC(=O)c1cccc(NC(=O)C(=O)N\N=C2/C(=O)N(CC=C)c3ccccc23)c1

InChI Key: InChIKey=VPOGUPFTDTXHJI-JWGURIENSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50489463   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transcription factor 7-like 2


(Homo sapiens (Human))
BDBM50489463
PNG
(CHEMBL2323031)
Show SMILES OC(=O)c1cccc(NC(=O)C(=O)N\N=C2/C(=O)N(CC=C)c3ccccc23)c1
Show InChI InChI=1S/C20H16N4O5/c1-2-10-24-15-9-4-3-8-14(15)16(19(24)27)22-23-18(26)17(25)21-13-7-5-6-12(11-13)20(28)29/h2-9,11H,1,10H2,(H,21,25)(H,23,26)(H,28,29)/b22-16-
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
1.60E+4n/an/an/an/an/an/an/an/a



University of Utah

Curated by ChEMBL


Assay Description
Inhibition of human beta-casein/Tcf4 interaction after 1 hr by fluorescence polarization assay


ACS Med Chem Lett 4: 306-11 (2013)


Article DOI: 10.1021/ml300367f
BindingDB Entry DOI: 10.7270/Q2CN76TG
More data for this
Ligand-Target Pair
Transcription factor 7-like 2


(Homo sapiens (Human))
BDBM50489463
PNG
(CHEMBL2323031)
Show SMILES OC(=O)c1cccc(NC(=O)C(=O)N\N=C2/C(=O)N(CC=C)c3ccccc23)c1
Show InChI InChI=1S/C20H16N4O5/c1-2-10-24-15-9-4-3-8-14(15)16(19(24)27)22-23-18(26)17(25)21-13-7-5-6-12(11-13)20(28)29/h2-9,11H,1,10H2,(H,21,25)(H,23,26)(H,28,29)/b22-16-
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
2.10E+4n/an/an/an/an/an/an/an/a



University of Utah

Curated by ChEMBL


Assay Description
Inhibition of human beta-casein/Tcf4 interaction after 1 hr by alphascreen assay


ACS Med Chem Lett 4: 306-11 (2013)


Article DOI: 10.1021/ml300367f
BindingDB Entry DOI: 10.7270/Q2CN76TG
More data for this
Ligand-Target Pair