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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transcription factor Jun' and Ligand = 'BDBM50092870'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transcription factor Jun


(Homo sapiens (Human))		BDBM50092870
PNG
(2-Methyl-4-trifluoromethyl-pyrimidine-5-carboxylic...)
Show SMILES Cc1ncc(C(=O)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F)c(n1)C(F)(F)F
Show InChI InChI=1S/C15H8F9N3O/c1-6-25-5-10(11(26-6)15(22,23)24)12(28)27-9-3-7(13(16,17)18)2-8(4-9)14(19,20)21/h2-5H,1H3,(H,27,28)
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PC cid
PC sid
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Similars
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Signal Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Concentration required to inhibit activator protein-1(AP-1) mediated transcriptional activation in human Jurkat T-cells

J Med Chem 43: 3995-4004 (2000)


BindingDB Entry DOI: 10.7270/Q26M363N
More data for this
Ligand-Target Pair