BindingDB PrimarySearch

Found 3 hits Enz. Inhib. hit(s) with Target = 'Transcription initiation factor TFIID subunit 1' and Ligand = 'BDBM50572130'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human))	BDBM50572130 (CHEMBL4864027) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.794	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human partial length TAF1 bromodomain 2 (D1521 to D1656 residues) expressed in bacterial expression system by BROMOscan assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00294 BindingDB Entry DOI: 10.7270/Q21V5JRX
TBA					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human))	BDBM50572130 (CHEMBL4864027) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of TAF1 bromodomain 2 (unknown origin) by TR-FRET assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00294 BindingDB Entry DOI: 10.7270/Q21V5JRX
TBA					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human))	BDBM50572130 (CHEMBL4864027) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of Halo-tagged histone H4 from NanoLuc-tagged TAF1 bromodomain 2 (unknown origin) expressed in HEK293 cells measured after 4 to 6 hrs by...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00294 BindingDB Entry DOI: 10.7270/Q21V5JRX
TBA					More data for this Ligand-Target Pair