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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 1' and Ligand = 'BDBM50344352'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM50344352
PNG
(1-(7-hydroxynaphthalen-1-yl)-3-(3-methoxyphenyl)ur...)
Show SMILES COc1cccc(NC(=O)Nc2cccc3ccc(O)cc23)c1
Show InChI InChI=1S/C18H16N2O3/c1-23-15-6-3-5-13(10-15)19-18(22)20-17-7-2-4-12-8-9-14(21)11-16(12)17/h2-11,21H,1H3,(H2,19,20,22)
PDB
MMDB

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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 8n/an/an/an/an/an/a



Bayer Yakuhin, Ltd

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPV1 expressed in CHO cells co-expressing aequorin and CRE-luciferase reporter gene assessed as inhibition of capsaicin...


Bioorg Med Chem Lett 21: 3354-7 (2011)


Article DOI: 10.1016/j.bmcl.2011.04.013
BindingDB Entry DOI: 10.7270/Q2NG4QXN
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Rattus norvegicus (rat))
BDBM50344352
PNG
(1-(7-hydroxynaphthalen-1-yl)-3-(3-methoxyphenyl)ur...)
Show SMILES COc1cccc(NC(=O)Nc2cccc3ccc(O)cc23)c1
Show InChI InChI=1S/C18H16N2O3/c1-23-15-6-3-5-13(10-15)19-18(22)20-17-7-2-4-12-8-9-14(21)11-16(12)17/h2-11,21H,1H3,(H2,19,20,22)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 8.60n/an/an/an/an/an/a



Bayer Yakuhin, Ltd

Curated by ChEMBL


Assay Description
Antagonist activity at rat TRPV1 expressed in CHO cells co-expressing aequorin and CRE-luciferase reporter gene assessed as inhibition of capsaicin-i...


Bioorg Med Chem Lett 21: 3354-7 (2011)


Article DOI: 10.1016/j.bmcl.2011.04.013
BindingDB Entry DOI: 10.7270/Q2NG4QXN
More data for this
Ligand-Target Pair