Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM26114 (CHEMBL88972 | pyridine carboxylate, 6b | pyridine-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents | PubMed | n/a | n/a | 5.18E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Zeneca Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of prolyl 4-hydroxylase by chromatographic determination of [14C]-succinic acid on ion-exchange minicolumna | J Med Chem 36: 3853-8 (1994) BindingDB Entry DOI: 10.7270/Q2RJ4HJV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM26114 (CHEMBL88972 | pyridine carboxylate, 6b | pyridine-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents | PubMed | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of prolyl 4-hydroxylase | J Med Chem 35: 800-4 (1992) BindingDB Entry DOI: 10.7270/Q25T3M3C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM26114 (CHEMBL88972 | pyridine carboxylate, 6b | pyridine-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents | PubMed | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of prolyl 4-hydroxylase activity by an indirect assay | J Med Chem 35: 804-7 (1992) BindingDB Entry DOI: 10.7270/Q2FF3R9D | |||||||||||
More data for this Ligand-Target Pair |