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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transmembrane protease serine 6' and Ligand = 'BDBM50236912'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transmembrane protease serine 6


(Homo sapiens (Human))		BDBM50236912
PNG
(CHEMBL4093566)
Show SMILES CC(C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CC12CC3CC(CC(C3)C1)C2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)c1nc2ccccc2s1 |r,TLB:19:20:23:27.25.26,THB:25:24:21:27.26.28,25:26:23.24.29:21,28:26:23:29.20.21,28:20:23:27.25.26|
Show InChI InChI=1S/C39H51N7O5S/c1-22(2)33(36(51)44-29(7-5-13-42-38(40)41)34(49)37-45-28-6-3-4-8-31(28)52-37)46-35(50)30(17-23-9-11-27(47)12-10-23)43-32(48)21-39-18-24-14-25(19-39)16-26(15-24)20-39/h3-4,6,8-12,22,24-26,29-30,33,47H,5,7,13-21H2,1-2H3,(H,43,48)(H,44,51)(H,46,50)(H4,40,41,42)/t24?,25?,26?,29-,30-,33-,39?/m0/s1
KEGG

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PC sid
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Similars
Article
PubMed
 6n/an/an/an/an/an/an/an/a



Universit£ de Sherbrooke

Curated by ChEMBL


Assay Description
Inhibition of recombinant human C-terminal V5-His-tagged matriptase-2 expressed in Drosophila S2 cells using Boc-Gln-Ala-ArgAMC as substrate measured...

Eur J Med Chem 129: 110-123 (2017)


Article DOI: 10.1016/j.ejmech.2017.02.006
BindingDB Entry DOI: 10.7270/Q2GB269P
More data for this
Ligand-Target Pair