Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Type-1 angiotensin II receptor (RABBIT) | BDBM50030732 (CHEMBL323506 | N-{3-[3-Butyl-4-(3-fluoro-2'(tert-b...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 0.840 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations. | J Med Chem 38: 3741-58 (1995) BindingDB Entry DOI: 10.7270/Q2Q81C35 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor (RABBIT) | BDBM50030732 (CHEMBL323506 | N-{3-[3-Butyl-4-(3-fluoro-2'(tert-b...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 0.840 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro ability of the compound to inhibit the binding of radioligand 125I[Sar1,IIe8]AII to AT1 receptor from rabbit aorta | Bioorg Med Chem Lett 4: 2787-2792 (1994) Article DOI: 10.1016/S0960-894X(01)80595-3 BindingDB Entry DOI: 10.7270/Q2WS8T68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor (Homo sapiens (Human)) | BDBM50030732 (CHEMBL323506 | N-{3-[3-Butyl-4-(3-fluoro-2'(tert-b...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibitory concentration of the compound against AT1 receptor from human adrenal tissues. | Bioorg Med Chem Lett 4: 2787-2792 (1994) Article DOI: 10.1016/S0960-894X(01)80595-3 BindingDB Entry DOI: 10.7270/Q2WS8T68 | |||||||||||
More data for this Ligand-Target Pair |