Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosinase (Homo sapiens (Human)) | BDBM240731 (US9422261, 4-(1- phenylethyl) benzene-1,3- diol) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | 2.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human His-tagged tyrosinase expressed in HEK 293 cells using L-DOPA as substrate by Lineweaver-Burk plot analysis | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00994 BindingDB Entry DOI: 10.7270/Q2PV6Q29 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Homo sapiens (Human)) | BDBM240731 (US9422261, 4-(1- phenylethyl) benzene-1,3- diol) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.31E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human His-tagged tyrosinase expressed in HEK 293 cells using L-DOPA as substrate by MBTH based assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00994 BindingDB Entry DOI: 10.7270/Q2PV6Q29 | |||||||||||
More data for this Ligand-Target Pair |