BindingDB PrimarySearch

Found 14 hits Enz. Inhib. hit(s) with Target = 'Tyrosinase' and Ligand = 'BDBM50219502'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tyrosinase (Homo sapiens (Human))	BDBM50219502 (4-hydroxyphenyl beta-D-glucopyranoside \| Arbutin \|...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard Curated by ChEMBL					Assay Description Inhibition of tyrosinase (unknown origin) assessed as reduction in melanin formation				Eur J Med Chem 171: 66-92 (2019) Article DOI: 10.1016/j.ejmech.2019.03.021 BindingDB Entry DOI: 10.7270/Q2X92FQN
Jamia Hamdard Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosinase (Homo sapiens (Human))	BDBM50219502 (4-hydroxyphenyl beta-D-glucopyranoside \| Arbutin \|...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
AmorePacific Corporation Curated by ChEMBL					Assay Description Inhibition of tyrosinase in Melan-a cells				Bioorg Med Chem Lett 17: 5462-4 (2007) Article DOI: 10.1016/j.bmcl.2007.07.032 BindingDB Entry DOI: 10.7270/Q2BZ65RK
AmorePacific Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50219502 (4-hydroxyphenyl beta-D-glucopyranoside \| Arbutin \|...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
AmorePacific Corporation Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse Melan-a cells by ELISA				Bioorg Med Chem Lett 20: 1162-4 (2010) Article DOI: 10.1016/j.bmcl.2009.12.021 BindingDB Entry DOI: 10.7270/Q2M045JZ
AmorePacific Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50219502 (4-hydroxyphenyl beta-D-glucopyranoside \| Arbutin \|...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	8.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16-F1 cells				Bioorg Med Chem 26: 6015-6022 (2018) Article DOI: 10.1016/j.bmc.2018.10.036 BindingDB Entry DOI: 10.7270/Q2SN0DC6
					More data for this Ligand-Target Pair
Tyrosinase (Homo sapiens (Human))	BDBM50219502 (4-hydroxyphenyl beta-D-glucopyranoside \| Arbutin \|...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.64E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of tyrosinase (unknown origin)				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosinase (Homo sapiens (Human))	BDBM50219502 (4-hydroxyphenyl beta-D-glucopyranoside \| Arbutin \|...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.64E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of tyrosinase (unknown origin)				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosinase (Homo sapiens (Human))	BDBM50219502 (4-hydroxyphenyl beta-D-glucopyranoside \| Arbutin \|...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of tyrosinase (unknown origin)				J Nat Prod 69: 1022-4 (2006) Article DOI: 10.1021/np0600853 BindingDB Entry DOI: 10.7270/Q21C1WPT
Shenyang Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50219502 (4-hydroxyphenyl beta-D-glucopyranoside \| Arbutin \|...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin synthesis after 1 hr				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50219502 (4-hydroxyphenyl beta-D-glucopyranoside \| Arbutin \|...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin synthesis after 1 hr				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50219502 (4-hydroxyphenyl beta-D-glucopyranoside \| Arbutin \|...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.55E+6	n/a	n/a	n/a	n/a	n/a	n/a
Catholic University of Daegu Curated by ChEMBL					Assay Description Inhibition of tyrosinase activity in alpha-MSH-stimulated mouse B16 cells using L-tyrosine as substrate				Bioorg Med Chem 19: 2168-75 (2011) Article DOI: 10.1016/j.bmc.2011.02.044 BindingDB Entry DOI: 10.7270/Q2K937TS
Catholic University of Daegu Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosinase (Homo sapiens (Human))	BDBM50219502 (4-hydroxyphenyl beta-D-glucopyranoside \| Arbutin \|...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6.50E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human His-tagged tyrosinase expressed in HEK 293 cells using L-DOPA as substrate by MBTH based assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00994 BindingDB Entry DOI: 10.7270/Q2PV6Q29
TBA					More data for this Ligand-Target Pair
Tyrosinase (Homo sapiens (Human))	BDBM50219502 (4-hydroxyphenyl beta-D-glucopyranoside \| Arbutin \|...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6.50E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human tyrosinase				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosinase (Homo sapiens (Human))	BDBM50219502 (4-hydroxyphenyl beta-D-glucopyranoside \| Arbutin \|...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6.50E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human tyrosinase				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosinase (Homo sapiens (Human))	BDBM50219502 (4-hydroxyphenyl beta-D-glucopyranoside \| Arbutin \|...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	3.20E+7	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibitory activity against mushroom tyrosinase				Bioorg Med Chem Lett 13: 2409-12 (2003) BindingDB Entry DOI: 10.7270/Q2HD7W6H
University of California Curated by ChEMBL					More data for this Ligand-Target Pair