Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Fyn' and Ligand = 'BDBM446704'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Fyn (Homo sapiens (Human))	BDBM446704 (9-methoxy-N-{3- methoxy-4-[3- (pyrrolidin-1-yl)pro...) Show SMILES COc1ccc2c(c1)-c1nc(Nc3ccc(CCCN4CCCC4)c(OC)c3)ncc1CC2(C)C Show InChI InChI=1S/C29H36N4O2/c1-29(2)18-21-19-30-28(32-27(21)24-17-23(34-3)11-12-25(24)29)31-22-10-9-20(26(16-22)35-4)8-7-15-33-13-5-6-14-33/h9-12,16-17,19H,5-8,13-15,18H2,1-4H3,(H,30,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...				US Patent US10688093 (2020) BindingDB Entry DOI: 10.7270/Q2Q81H48
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