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SMILES: COc1ccc2c(c1)-c1nc(Nc3ccc(CCCN4CCCC4)c(OC)c3)ncc1CC2(C)C

InChI Key: InChIKey=YLAJZJYICVYUHM-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 446704   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase Fyn


(Homo sapiens (Human))		BDBM446704
PNG
(9-methoxy-N-{3- methoxy-4-[3- (pyrrolidin-1-yl)pro...)
Show SMILES COc1ccc2c(c1)-c1nc(Nc3ccc(CCCN4CCCC4)c(OC)c3)ncc1CC2(C)C
Show InChI InChI=1S/C29H36N4O2/c1-29(2)18-21-19-30-28(32-27(21)24-17-23(34-3)11-12-25(24)29)31-22-10-9-20(26(16-22)35-4)8-7-15-33-13-5-6-14-33/h9-12,16-17,19H,5-8,13-15,18H2,1-4H3,(H,30,31,32)
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/a 8n/an/an/an/an/an/a



TBA

US Patent


Assay Description
The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...

US Patent US10688093 (2020)

More data for this
Ligand-Target Pair